Guide to Navigating this Research Archive
Here you will find research articles published by IDHP researchers that are related to our primary scientific foci: the interconnected mental health of children and their caregivers, the intergenerational impact of stressful experiences on mental and physical health, and interventions and other buffers that support family wellness.
In the right sidebar, you can search this archive by research topic, as well as by research study (you can read about each study on the Current Projects page). Each archive entry has a simple summary, the full scientific abstract, and a link to the full article. Most of the articles in this research archive are available open access (i.e., you can access it without a subscription). If you are trying to access an article and aren't able to see the full version, please email us at idhp@ucsf.edu, and we would be happy to assist.
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April 1, 2022
Child mental & behavioral health
Childhood adversity
Protective factors
This study looks at how the COVID-19 pandemic has affected families and children's well-being. The researchers found that when families experienced more pandemic-related difficulties, both caregivers and children experienced more stress, which was linked to lower life satisfaction for children. The study also found that social connections and engagement with family can protect children's well-being, especially for younger children, while anxiety and depression were risk factors for adolescents.
December 7, 2021
Biomarkers
Child mental & behavioral health
Childhood adversity
MAMAS/SEED Study
SEED Study
This study looked at how early life experiences can affect a child's mental and behavioral health. The researchers found that children who experienced adversity in the first 18 months of life were more likely to have heightened physiological response when faced with a challenge at age 3. Children with this heightened physiological response profile also had lower scores in executive functioning compared to those who had adaptive patterns across all systems.
October 20, 2021
CANDLE Study
Child mental & behavioral health
Childhood adversity
Protective factors
Stress during pregnancy
This study looked at how a mother's childhood trauma and stress during pregnancy affects her child's behavior at age 1. The study found that multiple types of maternal stress were associated with socioemotional-behavioral problems in children at age one. Importantly, findings also showed that maternal knowledge about child development can help protect against the negative effects of stress. This suggests that screening and early intervention for parents could help promote positive behavioral health in children.
August 12, 2021
Biomarkers
Child mental & behavioral health
Childhood adversity
CTRP-Health Study
Intervention effects
This study looked at how cortisol levels, measured through hair samples, are related to behavior problems in young children from low-income families. The researchers studied two groups of children: those who had experienced trauma and participated in therapy, and a community group of children from families experiencing high stress. They found that increases in cortisol over time were associated with greater improvements in child behavior problems, and that changes in hair cortisol levels over time may be more informative than looking at hair cortisol levels at one point in time.
July 20, 2021
Biomarkers
Childhood adversity
CTRP-Health Study
Stress during pregnancy
This study looked at how adversity during childhood and pregnancy affects the immune system in a sample of women who have experienced interpersonal violence. Researchers found that higher levels of adversity during childhood and pregnancy, but not total lifetime adversity, were associated with a type of immune system imbalance, which could lead to increased risk for chronic diseases. These findings suggest that experiencing adversity during childhood and pregnancy can have long-term impacts on health.
July 20, 2021
Child mental & behavioral health
Childhood adversity
CTRP-Health Study
Intervention effects
Maternal mental health
This study looked at how inflammation in the body might affect how well people respond to a behavioral treatment for depression and post-traumatic stress disorder (PTSD). The researchers measured the levels of certain proteins in the blood of mothers and their young children before treatment and found that those with higher levels of inflammation were less likely to improve with the treatment. This suggests that inflammation could be an important factor to consider when treating depression and PTSD.
May 18, 2021
CANDLE Study
Caregiving behaviors
Child mental & behavioral health
Childhood adversity
Maternal mental health
This study looks at how a mother's childhood experiences can affect her child's behavior. The researchers found that mothers who had negative childhood experiences were more likely to have children with internalizing behaviors. The study also looked at how maternal anxiety and parenting behaviors might mediate this relationship. The findings suggest that interventions that support specific parenting behaviors and address maternal anxiety may help reduce internalizing behaviors in children of mothers with adverse childhood experiences.
March 12, 2021
Biomarkers
Child mental & behavioral health
Childhood adversity
MAMAS/SEED Study
SEED Study
This study explored how different physiological systems work together to predict mental health in young children. Researchers identified different profiles of autonomic nervous system (ANS) and hypothalamic pituitary adrenal (HPA) axis functioning at 18 and 36 months of age. One profile which involved persistent heightened baseline ANS and HPA axis activity was associated with child internalizing (anxiety and depression) problems at age 3.
January 14, 2021
Biomarkers
Child mental & behavioral health
Childhood adversity
This study shows that the development of mental health problems in young children is influenced by both family adversity and physiological factors like cortisol levels and parasympathetic nervous system functioning. These findings emphasize the importance of considering multiple factors in understanding mental health and highlights the importance of family adversity prevention to make a positive impact on children's well-being.
December 1, 2020
Childhood adversity
This viewpoint article discusses the COVID-19 pandemic and its potential impact on families' wellbeing. The COVID-19 pandemic has created severe stressors and adverse childhood experiences (ACEs), particularly for ethnoracially and socioeconomically marginalized families. Families with a history of severe stress exposure may be particularly impacted by pandemic stressors. Researchers can use the scientific evidence of early childhood research to develop empirically supported interventions for adversity-exposed children and families during the pandemic.