Research

IDHP Research Summaries

Guide to Navigating this Research Archive

Here you will find research articles published by IDHP researchers that are related to our primary scientific foci: the interconnected mental health of children and their caregivers, the intergenerational impact of stressful experiences on mental and physical health, and interventions and other buffers that support family wellness. 

 

In the right sidebar, you can search this archive by research topic, as well as by research study (you can read about each study on the Current Projects page). Each archive entry has a simple summary, the full scientific abstract, and a link to the full article. Most of the articles in this research archive are available open access (i.e., you can access it without a subscription). If you are trying to access an article and aren't able to see the full version, please email us at [email protected], and we would be happy to assist. 

 

 

July 20, 2021
Biomarkers
Childhood adversity
CTRP-Health Study
Stress during pregnancy

Adversity in early life and pregnancy are immunologically distinct from total life adversity: Macrophage-associated phenotypes in women exposed to interpersonal violence

This study looked at how adversity during childhood and pregnancy affects the immune system in a sample of women who have experienced interpersonal violence. Researchers found that higher levels of adversity during childhood and pregnancy, but not total lifetime adversity, were associated with a type of immune system imbalance, which could lead to increased risk for chronic diseases. These findings suggest that experiencing adversity during childhood and pregnancy can have long-term impacts on health.
July 20, 2021
Child mental & behavioral health
Childhood adversity
CTRP-Health Study
Intervention effects
Maternal mental health

An immunogenomic phenotype predicting behavioral treatment response: Toward precision psychiatry for mothers and children with trauma exposure

This study looked at how inflammation in the body might affect how well people respond to a behavioral treatment for depression and post-traumatic stress disorder (PTSD). The researchers measured the levels of certain proteins in the blood of mothers and their young children before treatment and found that those with higher levels of inflammation were less likely to improve with the treatment. This suggests that inflammation could be an important factor to consider when treating depression and PTSD.